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The line drawings showing the courses of first episode and recurrent genital herpes are with permission of Dr L Corey Overview of genital herpes Cause HSV-1 and HSV-2 Site of infection Site of exposure HSV-1 acquired through orogenital contact HSV-2 through genital contact Incubation period One to two weeks Asymptomatic infection can occur Genital herpes is a lifelong chronic condition The virus becomes latent in a local sensory ganglion Main symptoms First episode Multiple painful genital ulcers starting as vesicles Constitutional symptoms, for example fever, malaise, headache, photophobia, and occasional retention of urine Recurrent episodes Less severe ulceration, sometimes preceded by prodromal symptoms, for example tingling Diagnosis Isolate virus from genital lesions by culture, polymerase chain reaction, or antigen detection Treatment of first episode (all for five days) Aciclovir (200 mg five times daily) Famciclovir (250 mg three times daily) Valaciclovir (500 mg twice daily) Episodic treatment (all for five days) Aciclovir (200 mg four times daily) Valaciclovir (500 mg twice daily) Famciclovir (125 mg twice daily) Suppressive therapy Aciclovir (400 mg twice daily) Valaciclovir (250 mg twice daily or 500 mg once daily) Famciclovir (250 mg twice daily) Further reading American Social Health Association mengapa situs forex diblokir


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